Naphth[1,2-b]oxirene-7-acetic acid, decahydro-1a,4-dimethyl-α-methylene-, (1aR,3aS,4R,7R,7aS,7bS)- - Names and Identifiers
Name | 4,5-Epoxyartemisinic acid
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Synonyms | 5-Epoxyartemisinic acid 4,5-Epoxyartemisinic acid Naphth[1,2-b]oxirene-7-acetic acid, decahydro-1a,4-dimethyl-α-methylene-, (1aR,3aS,4R,7R,7aS,7bS)-
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CAS | 92466-31-4
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Naphth[1,2-b]oxirene-7-acetic acid, decahydro-1a,4-dimethyl-α-methylene-, (1aR,3aS,4R,7R,7aS,7bS)- - Physico-chemical Properties
Molecular Formula | C15H22O3
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Molar Mass | 250.34 |
Density | 1.121±0.06 g/cm3(Predicted) |
Boling Point | 396.4±15.0 °C(Predicted) |
pKa | 4.32±0.11(Predicted) |
Storage Condition | 2-8℃ |
Naphth[1,2-b]oxirene-7-acetic acid, decahydro-1a,4-dimethyl-α-methylene-, (1aR,3aS,4R,7R,7aS,7bS)- - Introduction
4,5-epoxyartemisinic acid (4,5-epoxyartemisinic acid) is a compound that is the precursor molecule of artemisinin. It is a colorless crystal or white crystalline powder. The compound is mainly used in the production of artemisinin synthesis of semi-synthetic antimalarial drugs.
The preparation method of 4,5-epoxyartemisinic acid is usually obtained by reacting artemisinin with hydrogen peroxide to generate an epoxy compound. The reaction is generally carried out at an appropriate temperature and under appropriate reaction conditions.
Information on the safety of 4,5-epoxyartemisinic acid has been relatively little studied. However, as a chemical substance, regular safe operating procedures should be followed. Avoid contact with skin and eyes during handling and storage. Follow appropriate laboratory procedures and wear appropriate personal protective equipment, such as lab gloves, goggles, and laboratory tops. If there is an accident, should immediately seek professional help. Specific Safety information should refer to the relevant chemical Safety Data Sheet (Safety Data Sheet,SDS).
Last Update:2024-04-09 20:45:29